14 research outputs found
Mechanism of induction of anisocytosis
The mechanism of induction of anisocytosis was studied with experimental anemia of rabbits induced by blood depletion and phenylhydrazine chloride injection. The Price-Jones' curves of erythrocytes from anemic animals showed a large variety of red cell size, indicating the appearance of abnormally large sized cells. RNA contents of some reticulocytes in anemia were comparable to
those of polychromatic and late basophilic erythroblasts. The result proved that in severe anemia a large number of erythroblasts are denucleated at earlier maturation stages, in most cases at polychromatic, and some at late basophilic and some at orthochromatic stages, resulting in anisocytosis.</p
Leukemia autopsies in Japan
For the purpose to know whether the annual increase of leukemia incidence in Japan is due to some leukemogenic factors or due to the increased detection
rate, the authors made some statistical survey of autopsy cases in which the
diagnosis is reliable and not any type of leukemias escape the detection. The
results showed that acute leukemias, which are found mostly in younger age, is
actually increasing. In addition, it has been deduced that among the suspected
factors the increase in ionizing radiation will be one of the most probable factors
for the increase in leukemia incidence</p